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Remme DuFrenne was born in France. He married Anna unknown.Their son, William Fredrich, was born February 28, 1835 in Stommeln, Germany, near Koln. William died in Middleton, WI on July 18, 1892. He married Adelheid Nelles on July 23, 1858 in Madison, WI, daughter of Henricus Nelles and Anna Pesch from Pine Bluff, WI. Their children were, Anna b. 1860, who married a Phillip Schneider and a Frank Kalscheur, Fred W. b. 1864, married Emma Schroeder, Martin b. 1865 who married a Margaret unknown, Elizabeth, Lena, Charlie b. 1872, Willie b. 1873, Remy and Jacob.
In 1898 the DuFrene Brothers Store was prominent in Middleton. They engaged in general merchandising and stock buying as listed in the 1870 Directory.