Yes. Mary had two children with Howard. They were Charlotte B: July 1, 1853, D: May 31, 1856; and Charles Howard Wheaton Estabrooks, B: Dec. 11, 1854, Friendship,Fond du Lac Co.,WI, D: March 18, 1939. He was my great-grandfather and was known as "Big Grandpa". His son was smaller and more wirey.
Mary married Robert after Howard died in the cholera epidemic. His brother, Charles (who had married Elizabeth, Mary's sister) also died the same time of cholera. Robert already had children from his marriage to Lucinda Ketcham. With Mary, they had Lucinda Charlotte Estabrooks, B: November 17, 1857. I have her death date somewhere - visited her grave last summer in Pendleton, Oregon.