I'm not sure if Conrad Fleckenstein is related to Regina Fleckenstein, all I know is that she is the d/o Philip and Catherine Bergen Fleckenstein born May 10,1850. I have no information on any of her siblings. It is very possible that Conrad is related though, since I believe that Fryburg, Clarion County, PA is very close to Venago County. Fryburg is where Thomas Obenrader, one of Regina's sons settled. He was married to two of my great-grandfather's sisters.
I will recheck my notes to see if I can find any mention of a Conrad. If I can be of any other assistance, just let me know.