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The only Downing / Perigo marriage I have found was of a Jonathan Downing b. Jan 1677 Hatfield, MA s/o John & Mary (Bunce) Downing to Mary Perigo b. 1Apr1677 Lyme, CT d/o Robert & Marah (Wood) Perigo. Jonathan & Mary had children Mary, Jonathan & Elizabeth born at Groton, CT.
Jonathan had a brother, John Downing b. 29Oct1678 Hatfield, MA d. 1729 Groton, CT who had a wife Elizabeth ____? who died at Preston, CT 13Feb1735/6. John & Elizabeth had children Jonathan, Elizabeth, Sarah & Dorothy.
Mary Perigo had a sister, Elizabeth b. 1683 but I have found no evidence that she ever married or even lived to adulthood.