Your great-grandfather William Piepho (b. 1840) came to Des Moines in 1869. Check the 1870 IA census: Polk Co.; Des Moines East; Ward 5; page 252; listed under William Peopho. This should be his family.
His father was J.H. Conrad Piepho by his 2nd wife. Mother's name might be Mary Wilkening or Volkening. William was listed as a brother to Henry J. Piepho of Mankato, MN area in Henry's obit in 1924.
Hope this info helps! Do you have any info on William's wife's parents or when her birthday was?
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