According to the article, William Prentice of Carstairs, Isobel Prentice, born 1801, is not a sister of James Prentice, born 1798. However I do believe that they must be related in some way or other, though I don't really have anything to back that up.
I am wanting to know who the parents of your James Prentice are. I believe he married Janet Lockhart July 24 of 1774, as shown at PrenticeNet under OPR# 4210940. However You may be interested to know that Isobel Prentice is shown to be born October 16, 1791 under OPR# 5036674. Ihave it in my notes as well that she was born 1801.
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