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Hi Corrine. Isabel Saffell (b. 7/9/1857)was the sister of my Great Grandfather, Howard Saffell. Their parents were Mahlon Saffell and Joanna Mercer. Isabel had 5 siblings.(Howard, Marian, Annie, Mary, and Augustus) Isabel Saffell married Eugene Mercer and had 6 children (Nellie, Eugene, Belle, Beverly, Horace and Jean) If this is your Isabel, let me know. I have located another relative through this search who is also a descendent of Isabel Saffel and might know more about your direct line. I'll give you any info I have. Sincerely, Alane Bakalyar